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Take this medication regularly in order to get the most benefit from itTo help you remembertake it at the same time(seach dayDo not increase your dose or use this drug more often or for longer than prescribedYour condition will not improve any fasterand your risk of side effects will increase.
Patients with major depressive disorderMDDboth adult and pediatricmay experience worsening of their depression and/or the emergence of suicidal ideation and behaviorsuicidalityor unusual changes in behaviorwhether or not they are taking antidepressant medicationsand this risk may persist until significant remission occursSuicide is a known risk of depression and certain other psychiatric disordersand these disorders themselves are the strongest predictors of suicideThere has been a long-standing concernhoweverthat antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatmentPooled analyses of short-term placebo-controlled trials of antidepressant drugsSSRIs and othersshowed that these drugs increase the risk of suicidal thinking and behaviorsuicidalityin childrenadolescentsand young adultsages 1824with major depressive disorderMDDand other psychiatric disordersShort-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24there was a reduction with antidepressants compared to placebo in adults aged 65 and older.
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