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Increased risk of sedationrespiratory depression with concomitant other CNS depressantsegalcoholbenzodiazepinesopioidsTCAsmonitor closelyRisk of serotonin syndrome with serotonergic drugsegSSRIsSNRIsTCAstriptans5-HT 3 antagonistsopioidsmirtazapinetrazodonetramadolMAOIslinezolidIV methylene bluemonitor and discontinue if suspectedConcomitant with food may enhance CNS depressionMay cause falseBenedict’s test.
Metaxalone is a white to almost whiteodorless crystalline powder freely soluble in chloroformsoluble in methanol and in 96ethanolbut practically insoluble in ether or water.
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