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MEDROL Tabletslike prednisolone and other adrenocortical steroids is a potent therapeutic agent influencing the biochemical behavior of mostif not alltissues of the bodyBecause this anti-inflammatory steroid manifests little sodium-retaining activitythe usual early sign of cortisone or hydrocortisone overdosageieincrease in body weight due to fluid retentionis not a reliable index of overdosageHencerecommended dose levels should not be exceededand all animal patients receiving MEDROL should be under close medical supervisionAll precautions pertinent to the use of prednisolone apply to methylprednisoloneMoreoverthe veterinarian should endeavor to keep informed of current studies with MEDROL as they are reported in the veterinary literature.
Areas not suitable for injection are those that are anatomically inaccessible such as spinal joints and those like the sacroiliac jointswhich are devoid of synovial spaceTreatment failures are most frequently the result of failure to enter the synovial spaceIf failures occur when injections into the synovial spaces are certainas determined by aspiration of fluidrepeated injections are usually futileLocal therapy does not alter the underlying disease processand whenever possible comprehensive therapy including physiotherapy and what is triamterene-hctz. orthopedic correction should be employed.
Frequency not reportedBradycardiacardiac arrestcardiac arrhythmiascardiac enlargementcirculatory collapsecongestive heart failurefat embolismhypertensionhypertrophic cardiomyopathy in premature infantsmyocardial rupture following recent myocardial infarctionsyncopetachycardiathromboembolismthrombophlebitisvasculitisedemahypotensionRef]
Frequency not reportedExophthalmosglaucomaincreased intraocular pressureposterior subcapsular cataractsblindnesschorioretinopathyRef]
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