Studies show that weight loss with orlistat can decrease total and ldl cholesterol level of low-density lipoprotein-also known as bad cholesterol total -2.
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Weight-loss may affect glycemic control in patients with diabetes mellitusA reduction in dose of oral hypoglycemic medicatione.gsulfonylureasor insulin may be required in some patientssee Clinical Studies
Data chestionare stress elevi. from a pharmacokinetic interaction study showed that the absorption of beta-carotene supplement is reduced when concomitantly administered with XENICALXENICAL inhibited absorption of a vitamin E acetate supplementThe effect of XENICAL on the absorption of supplemental vitamin Dvitamin Aand nutritionally-derived vitamin K is not known at this timesee CLINICAL PHARMACOLOGYand WARNINGS AND PRECAUTIONS
Orlistat comes as a capsule and a nonprescription capsule to take by mouthIt is usually taken three times a day with each main meal that contains fatTake orlistat during a meal or up to 1 hour after a mealIf a meal is missed or does not have fatyou may skip your doseFollow the directions on your prescription label or the package label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake orlistat exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor or stated on the package.
Because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and betacarotenepatients should be counseled to take a multivitamin containing fat-soluble vitamins to ensure adequate nutritionsee WARNINGS AND PRECAUTIONSThe vitamin supplement should be taken at least 2 hours before or after the administration of XENICALsuch as at bedtime.
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